Lady Macbeth has read her husband's letter concerning his meeting with the three weird sisters and their predictions. One of the witches had prophesized that Macbeth would become the king. Lady Macbeth is pleased but she knows that Macbeth may be ambitious but he couldn't possibly carry out the murder of King Duncan which would probably be necessary to give him the crown. She knows that without her intervention Macbeth will never be a king. The murder plan has already formed in her head when she learns that King Duncan is visiting Inverness, their castle, tonight.
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