Best disease is a genetic disorder involving the eyes, also known as Vitelliform Macular Dystrophy type 2 (shortened as VMD2). It is a genetic disease in a heredity form of progressive macular dystrophy and macular degeneration, first founded in 1905.
The loss of vision or sharpness of the vision is not the only symptom of Best disease, but also like many other macular diseases, Best disease also affects either one or both eyes in central vision. People with Best disease, before the symptoms show, build up a large heap of fat-like substance that looks similar to an egg yolk in the area of the retina that enables central vision. The breaking down of the accumulation, not the arrangement, is related to the steady vision loss feature of Best disease.
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